Prognostic Model to Predict Post-Autologous Stem-Cell Transplantation Outcomes in Classical Hodgkin Lymphoma. Chan, FC, et al. Journal of Clinical Oncolocy, 2017.

  • Development of RHL30, a prognostic model that uses relapse biopsies in cHL to identify patients that will respond poorly to ASCT

Genetic profiling of MYC and BCL2 in diffuse large B-cell lymphoma determines cell-of-origin–specific clinical impact. Ennishi, D, et al. Blood, 2017.

  • Using SNP arrays, this study showed that MYC and BCL2 genetic alterations are dependent on cell of origin subtype, and that BCL2 mutations are significantly associated with inferior survival in R-CHOP treated patients

The impact of dual expression of MYC and BCL2 by immunohistochemistry on the risk of CNS relapse in DLBCL. Savage, K, et al. Blood, 2016.

  • This work demonstrates that DLBCLs with expression of both MYC and BCL2 by IHC have a poorer outcome after treatment with R-CHOP